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December 8, 2025BloodOpen Access

Association of obstructive sleep apnea with readmission and healthcare utilization in adults with sickle cell disease: A propensity-matched analysis of national readmission data

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Authors

RMRichard Mansour

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Overview

Retrospective analysis shows OSA significantly increases readmissions and healthcare utilization in adults with sickle cell disease, suggesting need for proactive management.

Key Points

  • OSA was associated with an 8-10% increase in readmissions for adults with sickle cell disease, indicating a significant clinical impact.
  • Adjusted risk ratios demonstrated that OSA led to higher resource utilization and longer hospital stays, with charges exceeding $400 million over five years.
  • The analysis employed propensity score matching to control for confounding variables, leading to robust comparisons between groups.
  • The findings underscore the importance of identifying and managing OSA in patients with sickle cell disease to mitigate hospital readmissions.

Cite This Study

Richard Mansour (2025) studied this question.

synapsesocial.com/papers/69362f7f4fa91c937236e53fhttps://doi.org/10.1182/blood-2025-2663
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