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October 12, 2025Open Access

The Emerging Role of LncRNAs in T-Cell Plasticity in Breast Cancer

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Authors

ADAastha DagarSSSandeep SinghVUVivek Uttam

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Overview

This review demonstrates the role of lncRNAs in T-cell plasticity and highlights immune escape in breast cancer.

Key Points

  • LncRNAs significantly influence T-cell infiltration, affecting tumor immunity.
  • Specific lncRNAs like LINC00472 and MIAT impact tumor interactions and immune escape mechanisms.
  • Regulatory roles of lncRNAs extend to cytokine and chemokine networks within the tumor microenvironment.
  • Insights into lncRNAs may guide personalized immunotherapies for improved breast cancer outcomes.

Cite This Study

Dagar et al. (2025) studied this question.

synapsesocial.com/papers/68ebabe3155248a327effda1https://doi.org/10.20944/preprints202510.0620.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long non-coding RNAs as key orchestrators of the tumor microenvironment in lung cancer2025 · 4 citations
  2. 2lncRNAs as Targetable Nodes of Oncogenic Networks Underlying Cancer Progression and Therapy Resistance2025 · 2 citations
  3. 3Dysregulation of lncRNAs in NK cells from breast cancer patients: implications for NK cell functions2025 · 3 citations
  4. 4Small non-coding RNAs: key regulatory factors and potential therapeutic targets in tumor immunity2025 · 8 citations
  5. 5Interactions between LncRNAs and MAPK signaling pathways in the pathogenesis of breast cancer2025