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September 12, 2025Frontiers in ImmunologyOpen Access

Small non-coding RNAs: key regulatory factors and potential therapeutic targets in tumor immunity

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Authors

WZWenfeng ZhanHDHaotian DongCYChengyuan Ye

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Overview

This review explores small non-coding RNAs in tumor immunity and their impact on immune escape mechanisms.

Key Points

  • Small non-coding RNAs play vital roles in regulating tumor immunity and shaping the tumor microenvironment.
  • These regulatory factors affect immune cell differentiation and checkpoint expression, aiding in tumor immune escape.
  • The review discusses potential clinical applications of small non-coding RNAs as biomarkers and therapeutic targets.
  • Emerging technologies may enhance the delivery and efficacy of therapies incorporating small non-coding RNAs.

Cite This Study

Zhan et al. (2025) studied this question.

synapsesocial.com/papers/68d41d9b713b0b5dfea6669fhttps://doi.org/10.3389/fimmu.2025.1639763
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regulatory mechanisms and emerging diagnostic and therapeutic opportunities of non-coding RNAs in tumorigenesis: a pan-cancer perspective2025
  2. 2Long non-coding RNAs as key orchestrators of the tumor microenvironment in lung cancer2025 · 4 citations
  3. 3The Mechanisms of Non-coding RNAs in Tumorigenesis and Cancer Progression2025
  4. 4Small Nucleolar RNAs as Emerging Players in Cancer Biology and Precision Medicine2025
  5. 5The Emerging Role of LncRNAs in T-Cell Plasticity in Breast Cancer2025