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October 10, 2025Jurnal Farmasi Sains dan PraktisOpen Access

POTENTIAL OF ROSELLA FLOWER EXTRACT KEFIR (HIBISCUS SABDARIFFA L.) IN REDUCING PANCREATIC β- CELL DAMAGE IN DIABETES MELLITUS MODEL RATS (RATTUS NORVEGICUS)

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Authors

VAViani AnggiJTJoni TandiDRDiana Rahmawati

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Implication

Experimental study demonstrates histopathological improvements in pancreatic β-cells in diabetic rats, suggesting protective effects.

Key Points

  • Administration of rosella flower extract kefir at 750 mg/kg BW improved pancreatic β-cell structure.
  • Histopathological analysis revealed a damage value of 0.4 in treated rats, indicating effective protection.
  • The study used male Rattus norvegicus models to assess the impact of diabetic induction and treatment.
  • Results suggest that rosella flower extract kefir may offer benefits for pancreatic health in diabetes.

Cite This Study

Anggi et al. (2025) studied this question.

synapsesocial.com/papers/68e861a57ef2f04ca37e470ahttps://doi.org/10.31603/pharmacy.v11i2.8197
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Also Consider

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  1. 1Kefir-derived exopolysaccharide ameliorates hyperglycemic control and beta cell integrity in a rat model of type 2 diabetes mellitus2025
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  3. 3THE EFFECT OF SOME ACTIVE COMPOUNDS OF THE AQUEOUS EXTRACT OF BASIL ON SOME BIOCHEMICAL PARAMETERS OF MALE RATS INDUCED WITH DIABETES2025
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  5. 5Beetroot Extract and Its Anti-Diabetic: Neuroprotective Effect in the Frontal Cortex and Cerebellar Cortex of Diabetic Wistar Rats2025