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September 5, 2025Tropical Journal of Natural Product ResearchOpen Access

The Effect of Crocus Sativus (Saffron) on the Liver Histology in Diabetic Rats Induced by a High-Fat High-Glucose Diet and Low Dose of Streptozotocin

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Authors

NNNadya NasrulIYIka YustisiaHSHimawan Sanusi

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Overview

Observational analysis shows saffron's potential to improve liver histology in diabetes, suggesting significant hepatoprotective benefits.

Key Points

  • Saffron extract significantly reduced cholesterol levels and improved liver histology in rats with diabetes.
  • Rats treated with saffron showed histological improvements compared to untreated diabetic controls, indicating beneficial effects.
  • Liver function markers, including aspartate and alanine aminotransferase, showed non-significant decreases, suggesting potential hepatoprotective effects.
  • The study involved 17 male Wistar rats subjected to high-fat diets and diabetes induction via streptozotocin.

Cite This Study

Nasrul et al. (2025) studied this question.

synapsesocial.com/papers/68c23966b210217d6477be7chttps://doi.org/10.26538/tjnpr/v9i8.55
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