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October 10, 2025Open Access

Molecular Pathology of Pancreatic Ductal Adenocarcinoma

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Authors

ASAkram ShalabyNSNavid SadriYXYue Xue

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Overview

Review summarizes genetic and epigenetic alterations in PDAC, indicating potential for targeted therapies.

Key Points

  • PDAC presents aggressive characteristics and poor prognosis, often diagnosed at advanced stages.
  • Recent advances in sequencing revealed crucial genetic alterations in PDAC, aiding in therapeutic approaches.
  • This review consolidates literature on PDAC molecular landscape and potential novel therapies.
  • Understanding heterogeneity in PDAC is vital for developing effective treatment strategies.

Cite This Study

Shalaby et al. (2025) studied this question.

synapsesocial.com/papers/68e861907ef2f04ca37e3ffbhttps://doi.org/10.20944/preprints202509.2579.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Importance of landscape exploration and progress in molecular therapies and precision medicine for pancreatic ductal adenocarcinoma2025
  2. 2Advances in pancreatic cancer early diagnosis, prevention, and treatment: The past, the present, and the future2025
  3. 3Targeting Advanced Pancreatic Ductal Adenocarcinoma: A Practical Overview2025
  4. 4Early Detection of Pancreatic Cancer: Current Advances and Future Opportunities2025
  5. 5Contemporary insights into the molecular mechanisms of development and genetic susceptibility to pancreatic cancer2025