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October 8, 2025Renal FailureOpen Access

Accessing the relationship between estimated glucose disposal rate and the incidence of the kidney disease: results from the China Health and Retirement Longitudinal Study

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Authors

XYXiaolan YeWLWentong LiuQTQinglai Tang

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Overview

Analysis reveals lower estimated glucose disposal rate increases kidney disease risks in older adults, suggesting a preventive focus may be beneficial.

Key Points

  • Higher estimated glucose disposal rate significantly reduces the risk of rapid kidney function decline.
  • Logistic regression indicated that each 1.0-SD increment in estimated glucose disposal rate lowered the odds of developing new-onset CKD.
  • Subgroup analyses showed a marked increase in kidney disease risk when estimated glucose disposal rate fell below a threshold of 10.405 mg/kg/min.
  • Predictive models incorporating estimated glucose disposal rate enhanced accuracy in identifying individuals at risk of kidney disease.

Cite This Study

Ye et al. (2025) studied this question.

synapsesocial.com/papers/68e5c1c76950a706b22b5ecehttps://doi.org/10.1080/0886022x.2025.2565408
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association between changes in estimated glucose disposal rate and composite kidney outcome in middle-aged and elderly individuals: a national cohort study2025
  2. 2Changes in the estimated glucose disposal rate and incident cardiovascular disease in patients with cardiovascular–kidney–metabolic syndrome stages 0–3: a prospective cohort study in China2025
  3. 3Associations between estimated glucose disposal rate and age-related ocular diseases in cardiovascular-kidney-metabolic syndrome stages 0–3: a large prospective cohort study2025 · 1 citations
  4. 4Association between the estimated glucose disposal rate and the occurrence of major cardiovascular events and stroke2025
  5. 5Changes in the Estimated Glucose Disposal Rate and Incident Cardiovascular Disease in Patients with Cardiovascular–Kidney–Metabolic Syndrome Stages 0–3: A Prospective Cohort Study in China2025