Changes in the estimated glucose disposal rate and incident cardiovascular disease in patients with cardiovascular–kidney–metabolic syndrome stages 0–3: a prospective cohort study in China
Prospective cohort study finds that reduced eGDR levels increase cardiovascular risk in CKM patients, suggesting monitoring may aid early intervention.
Key Points
Persistently low eGDR levels are associated with increased cardiovascular disease risk in patients with CKM syndrome.
During 3 years, 14.1% of participants experienced cardiovascular disease events, including heart disease and stroke.
K-means clustering was applied to measure eGDR changes, and logistic regression explored associations with cardiovascular risk.
Early monitoring of eGDR may help identify high-risk individuals among CKM syndrome patients for timely intervention.