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October 2, 2025GSC Biological and Pharmaceutical SciencesOpen Access

Effect of Gongronema latifolium and Telfairia occidentalis Leaf Fractions on Hepato-renal Function of Streptozotocin-induced Diabetic Wistar Rats

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Authors

NNNdifreke Enobong NtuenibokGEG. S. EffiongNENse Udoka Ebe

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Overview

Observational analysis showed improvements in hepato-renal function in diabetic rats, suggesting these leaf fractions may counteract toxicity.

Key Points

  • Significant improvement in liver and kidney functions was observed in diabetic rats treated with leaf fractions.
  • The ethyl acetate and methanol fractions from Gongronema latifolium and Telfairia occidentalis effectively reduced toxic biomarker levels.
  • A total of 54 Wistar rats were divided into 9 groups for treatment with various leaf fractions over 28 days.
  • Findings support the potential use of these plant fractions in managing diabetes-related organ toxicity.

Cite This Study

Ntuenibok et al. (2025) studied this question.

synapsesocial.com/papers/68de5d9c83cbc991d0a2043ehttps://doi.org/10.30574/gscbps.2025.32.3.0372
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Histomorphological Changes of Heart and Kidney of An Alloxan Induced Wister Rats Treated with Gongronema Latifolium Leaf Extract2024
  2. 2Morphological Alterations of the Kidney of Albino Rats Following Oral Administration of Aqueous and Methanolic Leaf Extract of <i>Gongronema latifolium</i>2025
  3. 3Effects of Ethanolic Leaf Extract of Telfairia Occidentalis on an Alloxan Induced Diabetic Male Wistar Rats2025
  4. 4Ethyl Acetate Fraction of Gynura procumbens Mitigates Hyperglycemia, Dyslipidemia, and Tissue Damage in Streptozotocin-Induced Diabetic Rats2025
  5. 5Investigation of changes in renal function parameters and organ histology of diabetic rats treated with &lt;i&gt;Pleurotus ostreatus&lt;/i&gt; ethanol extracts2025