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October 8, 2025Sciences of PharmacyOpen Access

Ethyl Acetate Fraction of Gynura procumbens Mitigates Hyperglycemia, Dyslipidemia, and Tissue Damage in Streptozotocin-Induced Diabetic Rats

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Authors

YMYani MulyaniMKMarita KaniawatiWAWidhya Aligita

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Overview

This analysis shows that ethyl acetate fraction improves blood glucose and lipid profiles in diabetic rats, suggesting its potential for diabetes management.

Key Points

  • The 150 mg/kg dose significantly reduced blood glucose by 61.3%, indicating its strong effect on hyperglycemia.
  • Total cholesterol decreased by 42.1% and triglycerides by 47.3%, showcasing improved lipid profiles among treatment groups.
  • Histological analysis revealed regeneration of pancreatic β-cells, which is crucial for restoring insulin production in diabetes.
  • These findings highlight the potential of Gynura procumbens as a natural agent for dyslipidemia and diabetes treatment.

Cite This Study

Mulyani et al. (2025) studied this question.

synapsesocial.com/papers/68e5c1c76950a706b22b5ec1https://doi.org/10.58920/sciphar0404371
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