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September 10, 2025

Histomorphological Changes of Heart and Kidney of An Alloxan Induced Wister Rats Treated with Gongronema Latifolium Leaf Extract

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NJNnodim Johnkennedy

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Overview

Observational analysis reveals significant improvements in heart and kidney alterations in alloxan-induced rats treated with Gongronema latifolium, highlighting potential therapeutic benefits.

Key Points

  • Significant restoration of cardiac and kidney tissues was observed in diabetic rats treated with Gongronema latifolium leaf extract.
  • Treatment with Gongronema latifolium resulted in a notable decrease in total cholesterol, triglycerides, LDL, and HDL levels compared to controls.
  • Alloxan-induced diabetic rats showed drastic glucose level reductions following treatment with Gongronema latifolium extract.
  • Results indicate that Gongronema latifolium has protective effects against diabetes-induced organ damage in the heart and kidneys.

Cite This Study

Nnodim Johnkennedy (2024) studied this question.

synapsesocial.com/papers/68c2443bb210217d647aad7dhttps://doi.org/10.64347/3064-710x/mccci.003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Morphological Alterations of the Kidney of Albino Rats Following Oral Administration of Aqueous and Methanolic Leaf Extract of <i>Gongronema latifolium</i>2025
  2. 2Effect of Gongronema latifolium and Telfairia occidentalis Leaf Fractions on Hepato-renal Function of Streptozotocin-induced Diabetic Wistar Rats2025
  3. 3Effect of ground coffee beans extract on the histological structures of alloxan induced diabetes female albino rats2025
  4. 4Antidiabetic potential of <i>Celtis tetrandra</i> Roxb. leaf extracts in alloxan-induced diabetic rats, lipid profile, and histopathological analysis of pancreas2025
  5. 5Effect of combined extract of leaves of Medicago sativum and seeds of Garcinia kola on biochemical indices of alloxan-induced diabetic rats.2025