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October 2, 2025

Effects of preoperative immunonutrition

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Authors

MPManivaasan PannirselvamZZZaıdı ZakarıaMWMichael Pak-Kai Wong

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Overview

Randomized controlled trial assesses immunonutrition effects on recovery in colorectal surgery patients, indicating limited benefits over standard nutrition.

Key Points

  • No significant differences were observed in hospital stay duration between the experimental and control groups.
  • Both groups recorded an equal incidence of 17.24% for infectious complications, including surgical site infections.
  • The study utilized a prospective randomized double-blinded approach to compare immunonutrition and standard oral supplements.
  • Findings suggest that preoperative immunonutrition may not enhance recovery outcomes over traditional nutrition in this patient demographic.

Cite This Study

Pannirselvam et al. (2025) studied this question.

synapsesocial.com/papers/68de5d9383cbc991d0a2005bhttps://doi.org/10.4240/wjgs.v17.i9.108127
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The impact of enteral immunonutrition on gut microbiota in colorectal cancer and gastric cancer patients in the preoperative period—preliminary results of randomized clinical trial2025
  2. 2Perioperative Oral Immunonutrient Regulation of Intestinal Barrier and Gut Microbiota in Patients with Gastric Cancer, a Randomized Controlled Clinical Trial2025 · 6 citations
  3. 3Perioperative Immunonutrition in Gastrointestinal Oncology: A Comprehensive Umbrella Review and Meta-Analysis on Behalf of TROGSS—The Robotic Global Surgical Society2025
  4. 4Nutritional status and postoperative outcomes in patients undergoing major resection for gastrointestinal cancer: a prospective cohort study2025
  5. 5The effect of preoperative oral carbohydrate administration on postoperative glucometabolic response, subjective well being and quality of life in patients undergoing colorectal surgery: a randomized controlled double-blind study2025 · 7 citations