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October 1, 2025Medical Journal of BabylonOpen Access

Assessment of Galectin-3 with Biochemical Changes in Patients with Chronic Kidney Disease

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Authors

DKDunia Abbas KhudhairSKS. KadhimHKHadeel Luay Kareem

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Overview

This case-control study shows significant links between galectin-3 levels and kidney function in CKD patients, suggesting potential diagnostic value.

Key Points

  • Galectin-3 concentration significantly increased in patients with chronic kidney disease compared to controls.
  • The area under the curve for galectin-3 in assessing kidney disease was found to be 77%, indicating substantial diagnostic potential.
  • Statistical methods confirmed a significant association between glomerular filtration rate and plasma Gal-3 levels in CKD patients.
  • This analysis involved 90 patients, providing a robust framework for understanding biochemical changes related to chronic kidney disease.

Cite This Study

Khudhair et al. (2025) studied this question.

synapsesocial.com/papers/68dd9537fe798ba2fc49960ahttps://doi.org/10.4103/mjbl.mjbl_763_24
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Role of Galectin-3 as a Biomarker in the Cardio-Renal-Metabolic Pathology Axis.2025
  2. 2Galectin‐3 and kidney function in type 2 diabetes treated with dapagliflozin: Analysis from DECLARE‐TIMI 582025
  3. 3Macrophage Derived Galectin-3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling.2025 · 16 citations
  4. 4Galectin 3 : possible tool for early detection of LV diastolic dysfunction in asymptomatic survivors of childhood, adolescent and young adult cancer2025
  5. 5Galectin-3/CD146 interaction promotes renal damage and systemic inflammation after acute kidney injury2025