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September 10, 2025European Heart Journal Supplements

Galectin 3 : possible tool for early detection of LV diastolic dysfunction in asymptomatic survivors of childhood, adolescent and young adult cancer

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Authors

SOSouhila OuabdesselamNBN. Ould BessiSBSalim Benkhedda

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Overview

Observational analysis found a positive correlation between galectin 3 levels and diastolic dysfunction in asymptomatic cancer survivors, indicating potential for screening.

Key Points

  • Galectin 3 significantly correlates with diastolic dysfunction, suggesting its role as a biomarker.
  • E/e’ ratio showed a correlation coefficient of r = 0.37 with p = 0.04, emphasizing its potential utility.
  • The study included 30 asymptomatic survivors averaging 24.9 years old with a mean time since treatment of 13.5 years.
  • Findings highlight the need for larger prospective studies to further validate galectin 3's diagnostic value.

Cite This Study

Ouabdesselam et al. (2025) studied this question.

synapsesocial.com/papers/68c23ed7b210217d64793a63https://doi.org/10.1093/eurheartjsupp/suaf083.168
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