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September 25, 2025Open Access

Transcatheter Aortic Valve Implantation in Patients with Chronic Kidney Disease: A Comprehensive Systematic Review and Qualitative Evidence Synthesis

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Authors

SPSmathi PiewluangPRPharittha Rattanapasert

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Overview

Comprehensive systematic review reports increased mortality and AKI in CKD patients post-TAVI, suggesting careful patient selection.

Key Points

  • CKD patients undergoing TAVI experienced higher mortality rates, revealing a relative risk of 1.28 to 1.65 for 30-day mortality.
  • Acute kidney injury incidence was significantly higher in CKD patients, with odds ratios ranging from 1.89 to 2.44 compared to non-CKD patients.
  • Many CKD patients showcased stable or improved renal function post-TAVI, indicating potential for successful outcomes despite higher risks.
  • Findings suggest that TAVI is appropriate for selected CKD patients, emphasizing the need for renal-protective strategies and follow-up care.

Cite This Study

Piewluang et al. (2025) studied this question.

synapsesocial.com/papers/68d5bd72dc445aa9033b0ce2https://doi.org/10.1101/2025.09.21.25336136
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluating Zero‐Contrast Transcatheter Aortic Valve Implantation (TAVI) for Patients With Renal Impairment: A Pooled Meta‐Analysis of 1505 Patients2025
  2. 2Temporal Dynamics of the Association Between Acute Kidney Injury and Mortality After Transcatheter Aortic Valve Implantation: Insights from Time-Varying and Landmark Survival Analyses2025
  3. 3TAVR vs. SAVR in Patients With Severe Aortic Stenosis and Chronic Kidney Disease Undergoing Dialysis: A Comprehensive Meta‐Analysis2026
  4. 4Impact of chronic kidney disease on short- and long-term outcomes after ventricular tachycardia ablation2026
  5. 5Comparative Efficacy and Safety of Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement in Patients With End-Stage Renal Disease: A Systematic Review and Meta-Analysis2025