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September 20, 2025Cardiology in Review

Comparative Efficacy and Safety of Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement in Patients With End-Stage Renal Disease: A Systematic Review and Meta-Analysis

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Authors

ZBZaryab BachaJJJaveria JavedFKFazia Khattak

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Overview

Systematic review shows TAVR may reduce in-hospital mortality and complications in ESRD patients, highlighting significant benefits over SAVR.

Key Points

  • TAVR demonstrated significantly lower in-hospital mortality with risk ratio of 0.52, suggesting it may be a safer option.
  • Additional benefits of TAVR included fewer complications and shorter hospital stays, indicating improved overall recovery.
  • The systematic review encompassed data from 7 cohort studies involving 15,462 patients, emphasizing the robustness of findings.
  • Despite geographic limitations and high heterogeneity, results support TAVR as a superior choice for high-risk ESRD patients.

Cite This Study

Bacha et al. (2025) studied this question.

synapsesocial.com/papers/68d439fa713b0b5dfea79d25https://doi.org/10.1097/crd.0000000000001064
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1TAVR vs. SAVR in Patients With Severe Aortic Stenosis and Chronic Kidney Disease Undergoing Dialysis: A Comprehensive Meta‐Analysis2026
  2. 2Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients2019 · 157 citations
  3. 3Transcatheter versus surgical aortic valve replacement for severe aortic stenosis in low-risk adults: a network meta-analysis2026
  4. 4Evaluating the Efficacy and Outcomes of Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement in Low‐ to Intermediate‐Risk Aortic Regurgitation Patients: A Comprehensive Clinical Comparison2026
  5. 5Transcatheter or Surgical Treatment of Patients With Aortic Stenosis at Low to Intermediate Risk2025 · 4 citations