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September 5, 2025Current Applied Science and TechnologyOpen Access

Evaluation of the Antioxidant and Antihyperglycemic Activity: A Comparative Study of Shallot (Allium ascalonicum L.) Peel and Bulb Ethanol Extracts

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Authors

MEM. Rifqi EfendiFDFifi Gus DwiyantiOOktavionita

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Overview

Comparative study reveals shallot peel extract is more effective than bulb extract for glycemic control in rats, suggesting its potential role in diabetes management.

Key Points

  • Shallot peel extract demonstrates superior antihyperglycemic activity compared to bulb extract in diabetic rats, indicating its suitability for diabetes treatment.
  • Total phenolic content in the peel is significantly higher (347.6 mg GAE/g) than in the bulb (78.7 mg GAE/g), showing its greater antioxidant potential.
  • The DPPH scavenging capacity of the peel extract (IC50 124.814 μg/mL) outperforms that of the bulb extract (IC50 1,712 μg/mL), indicating enhanced antioxidant activity.
  • Both extracts effectively reduce fasting blood glucose levels, with peel extract being most effective for glycemic control while the bulb has moderate effects.

Cite This Study

Efendi et al. (2025) studied this question.

synapsesocial.com/papers/68c239e5b210217d6477e6fdhttps://doi.org/10.55003/cast.2025.267970
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phytochemical Profiling and Dual In Vitro In Vivo Antidiabetic Assessment of Ethyl Acetate Fraction and Essential Oil From <scp><i>Allium ascalonicum</i></scp>2025
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  3. 3Evaluation of the Antidiabetic, Hypolipidemic and Hepatoprotective Effect of Allium sativum in Diabetic Rats2025
  4. 4Evaluation of Antioxidant and Hypoglycemic Properties of Citrus Peel Extracts and Their Implications for Diabetes Management2025
  5. 5Evaluation of the Hypoglycemic Potential of the Ethanolic Bulb Extract of Allium Chinense G. Don (Sibujing) on High-Glucose Induced Hyperglycemic Swiss Albino Mice2025