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September 23, 2025Journal of Clinical MedicineOpen Access

Recurrence of Glomerular Diseases (GN) After Kidney Transplantation: A Narrative Review

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Authors

AKAbbal KoiralaASAditi SinghDGDuvuru Geetha

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Overview

Narrative review explores GN recurrence risks and management in kidney transplant patients, highlighting proteinuria and treatment approaches.

Key Points

  • Recurrence of glomerular diseases significantly threatens kidney transplant function and longevity, impacting recipient health.
  • C3 glomerulopathy and FSGS show high recurrence rates, with risk linked to donor genetics, age, and proteinuria levels.
  • Comprehensive diagnostic strategies for recurrent glomerular diseases are crucial, including allograft biopsy and biomarker analysis.
  • Evolving treatment strategies focus on targeted therapies like rituximab and complement inhibitors to manage GN recurrence effectively.

Cite This Study

Koirala et al. (2025) studied this question.

synapsesocial.com/papers/68d43ed7713b0b5dfea7e660https://doi.org/10.3390/jcm14186686
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prophylactic interventions for focal segmental glomerulosclerosis recurrence after kidney transplantation: a systematic review and network meta-analysis2026
  2. 2Recurrent immunotactoid glomerulopathy in a kidney transplant recipient: Case report2025
  3. 3De Novo Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits (PGNMID) in a Renal Transplant Recipient2026
  4. 4Renal Involvement in Chronic Graft-Versus-Host Disease.2025
  5. 5Unravelling the Multifactorial Pathogenesis and Immune Cell Infiltrates in Transplant Glomerulopathy2025