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September 21, 2025International Journal of Pharmaceutical and Bio-Medical ScienceOpen Access

Effect Of Hydromethanolic Mangifera Indica Stem Bark and Leaf Extracts on Motor Coordination and Grip Strength in ECT-Induced Seizure in Male Wistar Rats

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Authors

BOBuduka Justice OttoIOIchechi Bright OwhorjiCOChibuike Obiandu

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Overview

This study demonstrates the neuroprotective effects of Mangifera indica extracts on motor coordination and grip strength in ECT-treated Wistar rats, suggesting potential clinical applications.

Key Points

  • Treatment with Mangifera indica extracts improved grip strength in ECT-induced seizure models.
  • ECT significantly impaired motor coordination, with beam walk latency increasing markedly compared to controls.
  • The study utilized male Wistar rats to assess the cognitive effects of hydromethanolic extracts on ECT deficits.
  • These findings highlight the potential of Mangifera indica as a therapeutic adjunct to mitigate ECT-related cognitive issues.

Cite This Study

Otto et al. (2025) studied this question.

synapsesocial.com/papers/68d43a0d713b0b5dfea7a712https://doi.org/10.47191/ijpbms/v5-i9-02
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Effect of Hydromethanolic Extracts of Mangifera Indica Stem Bark and Leaf on Learning and Memory in Electroconvulsive Therapy-Induced Seizures in Male Wistar Rats2025
  2. 2Tamarindus indica stem bark extract attenuates depression and spatial memory deficits in mice2025
  3. 3Ameliorative Effect of Mangifera indica (Mango) and its Effects on Some Haematological Profile of Male Brief Psychiotic Disorder Subjects of Enugu State2025
  4. 4Evaluation of the Effect of <i>Melissa officinalis</i> L. on Cognitive Impairments in major Depressive Disorder Patients Treated with Electroshock Therapy: A Randomized Clinical Trial2025
  5. 5COGNITIVE-ENHANCING EFFECT OF ETHYL ACETATE FRACTION OF ERYTHROPHLEUMIVORENSE STEMS BARK AGAINST KETAMINE-INDUCED MEMORY IMPAIRMENT IN MICE2025