Experimental analysis reveals tamarindus indica extract reduces depression and improves cognitive function in ketamine-exposed mice, suggesting a potential therapeutic role.
Key Points
Tamarindus indica stem bark extract improved depressive symptoms significantly in mice exposed to ketamine.
The highest dose of 400 mg/kg significantly reduced immobility in both the Tail Suspension Test and Forced Swimming Test.
Extract increased spontaneous alternation significantly in the Y maze test compared to the control group.
Presence of glycosides, saponins, phenols, and alkaloids was confirmed in the extract during phytochemical screening.