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September 16, 2025Journal of Shahrekord University of Medical SciencesOpen Access

Evaluation of the Effect of Melissa officinalis L. on Cognitive Impairments in major Depressive Disorder Patients Treated with Electroshock Therapy: A Randomized Clinical Trial

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Authors

MNMasoud NikfarjamKTKimia TorabiFKFatemeh Kaviani

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Overview

Randomized clinical trial reveals no significant improvement in cognitive impairments in major depressive disorder patients after ECT with Melissa officinalis therapy.

Key Points

  • No significant improvement in cognitive impairments was observed among patients after treatment with M. officinalis.
  • MMSE scores showed no statistically significant difference before or after the intervention in both groups.
  • This randomized clinical trial involved 70 patients treated with either M. officinalis or placebo over their ECT course.
  • Findings suggest that more extended treatment periods with M. officinalis should be explored for cognitive impairments.

Cite This Study

Nikfarjam et al. (2025) studied this question.

synapsesocial.com/papers/68d4263f713b0b5dfea6cb0ahttps://doi.org/10.34172/jsums.931
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