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September 20, 2025Frontiers in Cardiovascular MedicineOpen Access

Associations of vitamin D with coronary revascularization and heart rate variability in hypertensive patients

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Authors

ZLZongbin LiYZYuting ZouRLRuizhe Li

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Overview

This research shows vitamin D deficiency significantly increases coronary revascularization risk in hypertensive patients, suggesting the need for better management.

Key Points

  • Vitamin D deficiency significantly increases the risk of coronary revascularization in hypertensive patients.
  • Univariate and multivariate logistic regression analyses indicated a strong association with 25(OH)D levels.
  • HRV indices showed significant differences between vitamin D deficient and non-deficient groups, indicating impaired heart function.
  • Hypertensive patients with vitamin D deficiency exhibited higher aldosterone levels and greater aldosterone-to-renin ratios.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68d439f4713b0b5dfea79ac0https://doi.org/10.3389/fcvm.2025.1590701
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Systematic Review and Meta-analysis on the Involvement of Vitamin D in Left Ventricular Remodeling among Hypertensive Individuals2025
  2. 2Burden and Associated Factors of Vitamin D Deficiency Among Hypertensive and Normotensive Adults: A Hospital-Based Cross-Sectional Study in a Tertiary Care Hospital in Kathmandu, Nepal2025
  3. 3Cardiac Autonomic Dysfunction in Obstructive Sleep Apnea: The Hidden Role of Vitamin D Deficiency2025 · 1 citations
  4. 4Association between vitamin D deficiency and risk of venous thromboembolism: a matched cohort study of 139,690 patients2025 · 3 citations
  5. 5The association between heart rate variability and early kidney damage: The mediating role of blood lipid levels among hypertensive patients in a single-center cohort study2026 · 1 citations