Cationic Polyelectrolyte‐Polyphenol Complex Derived Gold Nanoparticles for Efficacious Anticancer Drug Delivery

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The synthesis of gold nanoparticles using a polyelectrolyte complex increased drug delivery efficacy.
Cytotoxicity analysis revealed significant responses in drug-sensitive and resistant cancer cell lines.
The method resulted in monodisperse and stable gold nanoparticles suitable for drug delivery applications.
Biocompatibility tests in a zebrafish model indicated safety for practical use in drug delivery.

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Instantaneous synthesis of gold nanoparticles enhances drug delivery efficacy in cancer cells, implying potential biocompatibility.

Sharma et al. (2025) studied this question.

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