September 10, 2025ACS Applied Bio Materials

Developing Biocompatible Chitosan-Stabilized Gold Nanoparticles with Anticancer and Antimicrobial Properties: A Computational and Experimental Approach

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Cs@AuNPs exhibited selective anticancer activity against MCF-7 cells with an IC50 of ∼100 μg/mL.
The nanoparticles displayed potent antibacterial activity against Escherichia coli and Staphylococcus aureus with inhibition zones of up to 15 mm.
Molecular dynamics simulations confirmed complex stability and favorable binding free energy calculations.
ADMET profiling indicated high intestinal absorption, suggesting potential for safe therapeutic applications.

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Implication

Experimentally developed chitosan-stabilized gold nanoparticles show promising anticancer and antimicrobial effects, suggesting a novel therapeutic avenue.

Cite This Study

Sana et al. (2025) studied this question.

synapsesocial.com/papers/68c24364b210217d647a73ce https://doi.org/10.1021/acsabm.5c01281

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Implication

Experimentally developed chitosan-stabilized gold nanoparticles show promising anticancer and antimicrobial effects, suggesting a novel therapeutic avenue.

Developing Biocompatible Chitosan-Stabilized Gold Nanoparticles with Anticancer and Antimicrobial Properties: A Computational and Experimental Approach

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Discussion

Implication

Cite This Study

Developing Biocompatible Chitosan-Stabilized Gold Nanoparticles with Anticancer and Antimicrobial Properties: A Computational and Experimental Approach

Key Points

Discussion

Implication

Cite This Study