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September 20, 2025General medicine and Clinical PracticeOpen Access

Antiretroviral Therapy and Sickle Cell Disease: Balancing Efficacy and Toxicity

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Authors

EOEmmanuel Ifeanyi Obeagu

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Overview

Observational analysis reveals the impact of antiretroviral therapy on pain crises and anemia in sickle cell disease, suggesting the need for careful management.

Key Points

  • Antiretroviral therapy can help manage complications in sickle cell disease, but may also introduce toxicity.
  • Individuals with sickle cell disease often experience acute pain crises, hemolysis, and organ damage due to sickled cells.
  • The management of sickle cell disease requires ongoing intervention to address anemia and related health issues.
  • The coexistence of HIV in sickle cell disease patients complicates treatment and management strategies.

Cite This Study

Emmanuel Ifeanyi Obeagu (2025) studied this question.

synapsesocial.com/papers/68d4390d713b0b5dfea78bf5https://doi.org/10.31579/2639-4162/262
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hematologic and Immunologic Crossroads: HIV in Sickle Cell Disease Patients2025
  2. 2Sickle cell disease: understanding pathophysiology, clinical features and advances in gene therapy approaches2025 · 14 citations
  3. 3Sickle Cell Disease: From Ancient Origins to Modern Breakthroughs in Gene Therapy2026
  4. 4Hemolysis and Vaso-Occlusive Crisis in Sickle Cell Disease: A Review2025
  5. 5Thrombosis risk in sickle cell disease with HIV co-infection: unraveling the complex interactions and clinical implications – a narrative review2025 · 1 citations