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September 19, 2025Cancer Epidemiology Biomarkers & Prevention

Abstract A075: Trends in colorectal cancer mortality among individuals aged 50 or less in the United States, 2012-2021

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Authors

MKMichael Rutalira Koko

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Overview

Retrospective analysis found increasing colorectal cancer mortality rates in young adults, suggesting urgent public health interventions.

Key Points

  • Colorectal cancer mortality rates increased by 31.3% among males aged 40-44 from 2012 to 2021.
  • The highest mortality rates for males aged 45-49 were recorded at 11.6 per 100,000 population in 2018.
  • For females, mortality rates peaked at 8.4 per 100,000 in 2014 and showed a 23.1% increase among ages 40-44.
  • The study highlights the necessity of improving colorectal cancer screening for younger populations.

Cite This Study

Michael Rutalira Koko (2025) studied this question.

synapsesocial.com/papers/68d43804713b0b5dfea77f0bhttps://doi.org/10.1158/1538-7755.disp25-a075
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Colorectal Cancer in the U.S., 1999–2021: Declining Rates, Rising Concerns, and Persistent Disparities2025
  2. 2Divergent age-specific trends in colorectal cancer mortality: A 22-year analysis of the emerging early-onset crisis.2026
  3. 3Incidence, prevalence, and temporal trends of colorectal cancer across age, sex, race, and ethnicity: A large real-world analysis.2026
  4. 4Abstract A131: Time tells a different story: Sex and age-related differences in 1-, 3-, and 5-year survival for early-onset CRC in Georgia2025 · 1 citations
  5. 5Mortality trends: Colorectal carcinoma associated with tobacco use as a cause of death in the United States—A CDC WONDER analysis (1999-2023).2026