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September 19, 2025Molecular Carcinogenesis

Screening and Validation of Genes Associated With Lysosomal‐Dependent Cell Death in Colorectal Cancer

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Authors

JZJianbin ZhuangCMChengquan MaMYMin Yang

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Overview

This analysis identifies candidate genes and elucidates risks in colorectal cancer, highlighting prognostic insights.

Key Points

  • A total of 37 candidate genes were identified that are linked to lysosomal-dependent cell death in colorectal cancer.
  • The risk model, derived from Cox regression analysis, showed significant diagnostic performance for colorectal cancer prognosis.
  • Enrichment analysis indicated differences in tumor immune microenvironment responses between high-risk and low-risk groups.
  • IL13RA2 was found to be expressed at higher levels in colorectal cancer patients compared to normal samples.

Cite This Study

Zhuang et al. (2025) studied this question.

synapsesocial.com/papers/68d437f0713b0b5dfea77469https://doi.org/10.1002/mc.70024
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