Revelation of prognosis and tumor microenvironment of colorectal cancer based on genes related to antibody-dependent cellular phagocytosis and single-cell landscape
Analysis reveals a novel prognostic model using antibody-dependent cellular phagocytosis genes in colorectal cancer, suggesting treatment pathways.
Key Points
The study establishes a prognostic model based on 7 ADCP-related genes for colorectal cancer patients, enhancing treatment guidance.
Using data from TCGA and GEO databases, the model effectively predicts prognosis as indicated by Kaplan-Meier survival curves and ROC analysis.
Functional enrichment analysis shows significant signaling pathways linked to high-risk scores in colorectal cancer cells, suggesting treatment avenues.
The analysis identifies potential therapeutic agents such as Dasatinib and Tegafur, which might improve treatment outcomes in colorectal cancer patients.