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September 19, 2025Doctor RuOpen Access

Features of the Metabolomic Profile in Gestational Diabetes Mellitus

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Authors

LGL.G. GazaryanPeoples' Friendship University of RussiaIOIrina Mikhaylovna OrdiyantsPeoples' Friendship University of RussiaМLМ. G. LebedevaPeoples' Friendship University of Russia

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Implication

Observational study shows altered metabolomic profiles in gestational diabetes, indicating potential biomarkers.

Key Points

  • Reduced total urinary amino acid content was observed in women with gestational diabetes mellitus (GDM).
  • Concentrations of valine, lysine, and glutamine showed significant differences between GDM and control groups.
  • The study involved 24 participants with GDM and 21 without, analyzing 26 amino acids in urine samples.
  • Findings suggest urine metabolites could serve as biomarkers, enhancing understanding of GDM etiology.

Cite This Study

Gazaryan et al. (2025) studied this question.

synapsesocial.com/papers/68d43706713b0b5dfea76dc3https://doi.org/10.31550/1727-2378-2025-24-5-63-67
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Amino Acid Profile Alterations in the Mother–Fetus System in Gestational Diabetes Mellitus and Macrosomia2025 · 1 citations
  2. 2Metabolomic Signatures of Transitional Breast Milk in Gestational Diabetes Mellitus: A Case–Control Study Assessing the Impact of Insulin Therapy2025 · 3 citations
  3. 3Early biochemical markers and screening diagnosis of gestational diabetes mellitus2025
  4. 4Sonographic and Biochemical Markers in Gestational Diabetes Mellitus: A Prospective Cohort Study at a Tertiary Hospital in Greece2025
  5. 5Early metabolic biomarkers in neonates of diabetic mothers: predictive insights from amino acid and acylcarnitine profiling2025 · 2 citations