September 18, 2025Frontiers in ImmunologyOpen Access

Serum Krebs von den Lungen-6 before treatment predicts the prognosis of lung cancer in Asian populations: a systematic review and meta-analysis

View Full Paper

Ask AI

Bookmark

High serum KL-6 levels before treatment indicate shorter progression-free survival in lung cancer patients.
The pooled hazard ratio for overall survival (OS) was 1.76, with significant associations found at KL-6 levels above 500 U/mL.
Subgroup analysis showed elevated KL-6 levels predict OS for lung cancer patients without interstitial lung disease.
Electrochemiluminescence immunoassay demonstrates superior predictive value for serum KL-6 compared to enzyme-linked immunosorbent assay.

Discussion

No takes yet. Share an insight, caveat, or question.

Meta-analysis found high serum KL-6 levels predict worse outcomes in lung cancer patients, suggesting its potential as a prognostic biomarker.

Huang et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Meta-analysis found high serum KL-6 levels predict worse outcomes in lung cancer patients, suggesting its potential as a prognostic biomarker.