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September 17, 2025Journal of Drug Design and Medicinal ChemistryOpen Access

Comprehensive Overview of Eugenol: Focusing on Sources, Structure, Pharmacological Activities, Mechanisms of Action, Safety Profile, and Applications

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Authors

AFAhmad FaruqIIIbrahim M. Ibrahim

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Overview

This review uncovers the pharmacological activities of eugenol in therapeutic applications, suggesting new delivery methods for improved efficacy.

Key Points

  • Eugenol demonstrates diverse pharmacological activities such as antioxidant and anti-inflammatory effects, highlighting its therapeutic potential.
  • Key evidence indicates that eugenol's therapeutic actions include inhibition of inflammatory enzymes and regulation of oxidative stress.
  • This overview details eugenol's mechanisms of action, drug delivery advancements, and its limitations, particularly concerning solubility and bioavailability.
  • The findings imply that ongoing research on micro/nano-formulations offers promising solutions to enhance eugenol's clinical applications.

Cite This Study

Faruq et al. (2025) studied this question.

synapsesocial.com/papers/68d42c5f713b0b5dfea70120https://doi.org/10.11648/j.jddmc.20251103.11
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects2025
  2. 2Development of eugenol derivatives with 5-LOX inhibitory activity2025
  3. 3Species of the Genus <i>Eugenia</i>: Bioactive Effects and Toxicity2025
  4. 4Multifunctional Activity of Syzygium aromaticum Extracts Against Candida albicans: Free Radicals, Membrane Permeabilization and Cdr1p Localization2025 · 1 citations
  5. 5Synthesis and Multiscale In Silico Assessment of Eugenol‐Derived Isoxazole‐Isoxazolines for VEGFR2 Inhibition2026