September 12, 2025Open Access

Possible Targets for the Treatment of Alzheimer’s Disease – A Narrative Review

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Narrative review synthesizes evidence on therapies for Alzheimer's disease, highlighting cognitive decline and clinical outcomes.

Cognitive decline in Alzheimer's can improve with therapies, but benefits may diminish over time.
Lecanemab and donanemab significantly reduced cognitive decline by about 27% and 35%, respectively.
Randomized controlled trials and systematic reviews were prioritized to gather robust evidence for treatment options.
Future treatments may focus on biomarker-driven diagnosis and multimodal therapy combinations to enhance efficacy.

Khalid et al. (2025) studied this question.

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