Current Strategies for Improvements in the Treatment of Alzheimer's Disease

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Review shows new targets and therapies may improve cognitive function in Alzheimer's patients, suggesting ongoing research is crucial.

Drugs targeting β-amyloid and phosphorylated tau have shown limited efficacy in phase 3 trials for Alzheimer's disease.
Significant improvements in cognitive function have been observed in animal models but not consistently in human trials.
Gene therapy is a promising avenue aiming to restore neuronal function, yet immediate benefits for patients remain unclear.
Understanding inflammation and oxidative stress may lead to the development of new drug classes for Alzheimer's disease.

Alharbi et al. (2024) studied this question.

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