Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 12, 2025Risk Management and Healthcare PolicyOpen Access

Clinical Characteristics and Risk Factors for Progressive Pulmonary Fibrosis in Primary Sjögren’s Syndrome: A Case-Control Study

View Full Paper
Ask AI
Bookmark
Share

Authors

JDJianjun DiaoLQLin QiaoXDXinwang Duan

Discussion

Loading...

Member takes

Overview

Case-control study identifies clinical features and risk factors for pulmonary fibrosis in Sjögren's syndrome patients, suggesting important predictors.

Key Points

  • The study finds that a baseline DLCO% < 60% is an independent risk factor for progressive pulmonary fibrosis.
  • Participants with progressive pulmonary fibrosis show reduced forced vital capacity and lung carbon monoxide diffusion capacity.
  • The predictive model has a strong area under the curve of 0.821, indicating good performance in distinguishing between PPF and non-PPF groups.
  • Significant differences in clinical characteristics, such as expectoration and crackles on examination, were observed between the two groups.

Cite This Study

Diao et al. (2025) studied this question.

synapsesocial.com/papers/68d41bfb713b0b5dfea65064https://doi.org/10.2147/rmhp.s533705
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of patients diagnosed with primary Sjogren's syndrome with and without pulmonary involvement.2025
  2. 2[Research status of diagnosis, treatment and prognosis of primary Sjögren's syndrome-associated interstitial lung disease].2025
  3. 3The structure and gender characteristics of progressive pulmonary fibrosis according to retrospective research2025
  4. 4Evolving Concepts in Progressive Pulmonary Fibrosis: A Clinical Update2025
  5. 5A NEW BIOMARKER IN SJOGREN’S SYNDROME? PAN-IMMUNE-INFLAMMATION VALUE AND ITS CLINICAL APPLICABILITY2025 · 1 citations