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September 5, 2025Journal of RespirationOpen Access

Evolving Concepts in Progressive Pulmonary Fibrosis: A Clinical Update

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Authors

MNMaría Noboa-SevillaFHFernanda Hernández‐GonzálezSCSandra Cuerpo-Cardeñosa

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Overview

This review updates criteria for defining progressive pulmonary fibrosis in patients with interstitial lung disease, highlighting challenges in clinical management.

Key Points

  • Progressive pulmonary fibrosis is linked to worse quality of life and higher mortality rates in patients.
  • Current criteria for PPF include worsening respiratory symptoms and decline in pulmonary function tests over one year.
  • Challenges in implementing PPF criteria in practice have been identified, along with the need for improved assessment tools.
  • Future directions include standardizing pulmonary function testing and enhancing quantitative radiological evaluation methods.

Cite This Study

Noboa-Sevilla et al. (2025) studied this question.

synapsesocial.com/papers/68c239e5b210217d6477e4c3https://doi.org/10.3390/jor5030014
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  1. 1Initiation of antifibrotic treatment in fibrosing interstitial lung disease: is the clock ticking till proven progression?2025
  2. 2ADVANCES IN THE DIAGNOSIS AND TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS - A LITERATURE REVIEW2025
  3. 3A Comprehensive Review on Pulmonary Fibrosis (PF): Histological Spectrum, Diagnosis, Risk Factors, Pathogenesis, Molecular Pathophysiology, and Current Treatment Options2025
  4. 4The structure and gender characteristics of progressive pulmonary fibrosis according to retrospective research2025
  5. 5Combined pulmonary fibrosis and emphysema: a narrative review2025