Retrospective analysis finds no strong correlation between PIV and disease activity in Sjogren's syndrome, indicating its potential as a complementary marker.
Key Points
The study indicates PIV may serve as an indirect indicator of inflammatory activity in sjogren's syndrome, though not as a standalone marker.
A weak, non-significant positive correlation was found between PIV and disease activity (ESSDAI), with a significant correlation to ESR.
Participants included 63 patients with sjogren's syndrome and 52 controls, highlighting the need for larger studies to confirm findings.
PIV showed an AUC of 0.675 in predicting higher disease activity, suggesting it may help in identifying patients with systemic activity.