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September 10, 2025Expert Opinion on Drug DeliveryOpen Access

From stem cell transplantation to stem cell-based drug delivery systems targeting hematological malignancies: recent advances and clinical considerations

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Authors

PZPing ZhangRLRuyi LinJGJianqing Gao

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Overview

Review reveals stem cell-based drug delivery strategies improve treatment of hematological malignancies, suggesting solutions to GVHD.

Key Points

  • Stem cell-based drug delivery improves targeting of hematological malignancies, enhancing local treatment outcomes.
  • Clinical challenges in hematopoietic stem cell transplantation include relapse and graft-versus-host disease.
  • An examination of stem cell types underscores the promise of mesenchymal stem cells and induced pluripotent stem cells.
  • Future research must address safety concerns and advance stem cell engineering for effective therapies.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68d413ee713b0b5dfea61891https://doi.org/10.1080/17425247.2025.2556320
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  5. 5Gene-edited hematopoietic stem cells for leukemia and lymphoma treatment: a systematic review of preclinical and translational evidence2025 · 4 citations