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July 12, 2025Stem Cell Reviews and ReportsOpen Access

Stem Cell for Cancer Immunotherapy: Current Approaches and Challenges

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Authors

ZAZainab AlaliUFUmme Tamanna FerdousANAlexis Nzila

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Overview

Review highlights stem cell roles in cancer immunotherapy and challenges faced, suggesting CRISPR may enhance treatments.

Key Points

  • Stem cell-based immunotherapy harnesses the immune system to target and eliminate cancer cells.
  • Clinical applications of stem cells include developing engineered immune cells like CAR-T and NK cells.
  • Challenges exist, such as safety risks, immune system evasion by tumors, and regulatory barriers.
  • Advancements like CRISPR gene editing aim to improve the effectiveness of personalized stem cell therapies.

Cite This Study

Alali et al. (2025) studied this question.

synapsesocial.com/papers/689a02afe6551bb0af8cbecchttps://doi.org/10.1007/s12015-025-10933-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Induced Pluripotent Stem Cell-Based Cancer Immunotherapy: Strategies and Perspectives2025 · 5 citations
  2. 2DEVELOPMENT OF STEM CELL-BASED CANCER THERAPY STRATEGIES2024
  3. 3The Application of iPSCs in Tumour Immunotherapy.2025
  4. 4Pharmacological Strategies in Cancer Immunotherapy: Advancing Immune Checkpoint Inhibitors, CAR-T Cell Therapies, and Cancer Vaccines2025
  5. 5Immunotherapy in Oncology: A Beginner’s Perspective on Breakthroughs and Challenges2025