Topical Heparin in Burns: A Systematic Review and Meta-analysis of Randomized Controlled Studies

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Systematic review analyzes topical heparin's effects on pain and infection rates in burns, suggesting mixed outcomes due to bias.

Topical heparin significantly reduced local wound infections by 60% in burn patients.
The analysis included seven RCTs involving 503 patients, highlighting the need for more rigorous studies.
Pain scores decreased with topical heparin, though results varied, indicating potential sensitivity among patients.
All included studies exhibited high risk of bias, indicating limitations in supporting broad clinical application.

Nassar et al. (2025) studied this question.

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