Tranexamic Acid in Patients Undergoing Burn Surgery: An Updated Meta-Analysis

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Meta-analysis demonstrates tranexamic acid reduces blood loss and PRBC transfusions in burn patients, suggesting its utility in surgical settings.

Tranexamic acid was associated with a significant reduction in total blood loss during burn surgery.
The analysis of seven studies revealed a decrease in total PRBC transfusions and the incidence of intraoperative transfusion.
No significant differences were found in postoperative hemoglobin levels or length of hospital stay.
Further high-quality research is needed to validate the effectiveness of tranexamic acid in this patient population.

Jian-zhen et al. (2025) studied this question.

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Meta-analysis demonstrates tranexamic acid reduces blood loss and PRBC transfusions in burn patients, suggesting its utility in surgical settings.