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September 10, 2025Scientific ReportsOpen Access

Phenotypic characterisation and prevalence of carbapenem-resistant Enterobacterales in a tertiary care centre in Bihar India

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Authors

PDPramurtajyoti DebBarmaPKPrathyusha KokkayilASAsim Sarfraz

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Overview

Cross-sectional study reveals a high prevalence and concerning antibiotic resistance in Enterobacterales, highlighting urgent public health needs.

Key Points

  • Carbapenem-resistant Enterobacterales showed a prevalence of 32.97% among 3421 isolates screened.
  • Inpatients exhibited a significantly higher resistance rate of 47.74% compared to 14.48% in outpatients.
  • Dominant phenotypes included Class B carbapenemases, observed in 70% of Escherichia coli and 55% of Klebsiella pneumoniae.
  • The findings suggest an urgent need for interventions like screening and antibiotic stewardship to manage CRE spread.

Cite This Study

DebBarma et al. (2025) studied this question.

synapsesocial.com/papers/68c24317b210217d647a5bcfhttps://doi.org/10.1038/s41598-025-04460-z
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  1. 1Carbapenem resistence and Carbapenemase classification of Enterobacteriaceae in Intensive Care Unit: A cross-sectional study2025
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  3. 3Detection of carbapenemase production in Enterobacterales by mCIM and eCIM: a tertiary care hospital study2025
  4. 4A-254 Molecular characterization of carbapenem and colistin resistance in isolates causing UTI at an outpatient setting of a tertiary care hospital2025 · 1 citations
  5. 5<xhtml:span xmlns:xhtml="http://www.w3.org/1999/xhtml" xml:lang="en">Phenotypic Characterization of Carbapenem-Resistant Enterobacteriaceae  across One Health Interface </xhtml:span>2025