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September 10, 2025Iranian Journal of MicrobiologyOpen Access

Detection of carbapenemase production in Enterobacterales by mCIM and eCIM: a tertiary care hospital study

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Authors

TSTawheed Ahmad ShafiAMAnjum Ara MirSRShagufta Roohi

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Overview

Observational study assessed carbapenemase detection in 160 CRE isolates, indicating critical surveillance needs.

Key Points

  • Among 471 tested isolates, 33.9% were carbapenem-resistant, highlighting a significant healthcare challenge.
  • mCIM identified 60.6% of carbapenem-resistant isolates as positive for carbapenemase production.
  • eCIM testing revealed that 85.5% of mCIM positive isolates produced metallo-beta-lactamases.
  • High rates of multi-drug resistance were noted among both MBL and serine carbapenemase producers.

Cite This Study

Shafi et al. (2025) studied this question.

synapsesocial.com/papers/68c23e02b210217d64790da7https://doi.org/10.18502/ijm.v17i4.19227
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Also Consider

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  1. 1Carbapenem resistence and Carbapenemase classification of Enterobacteriaceae in Intensive Care Unit: A cross-sectional study2025
  2. 2Paradoxical carbapenemase activity detected by modified carbapenemase inactivation (mCIM) method in <i>Citrobacter sedlakii</i>2025
  3. 3Phenotypic characterisation and prevalence of carbapenem-resistant Enterobacterales in a tertiary care centre in Bihar India2025
  4. 4Prevalence, molecular carbapenemase detection, and antibiotic resistance of carbapenem-resistant <i>Enterobacterales</i> in a tertiary care hospital in East Jerusalem (2019–2023): a retrospective study2025
  5. 5Carbapenem-Resistant Enterobacterales in Indian ICU Patients: Molecular Insights, Risk Factors, and Clinical Impact.2025