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September 10, 2025

Phenotypic Characterization of Carbapenem-Resistant Enterobacteriaceaeacross One Health Interface

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Authors

AOAbidemi OjoSASeun Owolabi AdebajoAOA.R. Oloyede

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Implication

Analysis identifies high rates of multidrug resistance and carbapenemase production in tuberculosis patients and animals, suggesting critical public health implications.

Key Points

  • A significant 70.2% of isolated enterobacteriaceae were carbapenemase-producing, indicating serious public health concerns.
  • Commonly found species included Klebsiella pneumoniae at 66.7% in sputum and 100% in fecal samples, highlighting its prevalence.
  • Ceftizidime resistance reached 100% in sputum samples, emphasizing the alarming level of multidrug resistance among tested antibiotics.
  • The interconnectivity of humans, animals, and the environment was evident, reinforcing the One Health approach to address this issue.

Cite This Study

Ojo et al. (2025) studied this question.

synapsesocial.com/papers/68c23b4ab210217d64783d77https://doi.org/10.1099/acmi.0.000809.v3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phenotypic characterisation and prevalence of carbapenem-resistant Enterobacterales in a tertiary care centre in Bihar India2025 · 6 citations
  2. 2Carbapenem resistance and carbapenemase classification of Enterobacteriaceae in intensive care unit: a cross-sectional study2025
  3. 3Molecular characterization of blaNDM and other carbapenemases genes among carbapenem-resistant Enterobacterales from community-and hospital- acquired urinary tract infections2025 · 2 citations
  4. 4Detection of carbapenemase production in Enterobacterales by mCIM and eCIM: a tertiary care hospital study2025 · 1 citations
  5. 5Assessment of Carbapenem-Resistant Enterobacteriaceae and Other Gram-Negative Bacteria on Intensive Care Unit Surfaces and Among Healthcare Workers at Tobruk Medical Center2025