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September 10, 2025Clinical Laboratory

Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type with Immune Thrombocytopenia as the First Primary Presentation

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Authors

YSYingying SunCLChunyan LiuMichigan Technological UniversityHWHuaquan WangTianjin Medical University General Hospital

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Implication

Case report highlights rare primary presentation of non-Hodgkin lymphoma as immune thrombocytopenia, suggesting careful evaluation.

Key Points

  • Patient initially misdiagnosed with immune thrombocytopenia, but later revealed primary cutaneous diffuse large B-cell lymphoma.
  • Complete remission of immune thrombocytopenia achieved with cyclophosphamide before lymphoma symptoms emerged.
  • Skin biopsy confirmed PCDLBCL-LT after development of erythematous plaques covering the body.
  • CHOP regimen treatment improved patient's condition significantly following initial presentation.

Cite This Study

Sun et al. (2025) studied this question.

synapsesocial.com/papers/68c24236b210217d647a2eeahttps://doi.org/10.7754/clin.lab.2025.250156
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Unexpected Diagnosis in a Cutaneous Tumoral Lesion: Primary Cutaneous Leg-Type B-Cell Lymphoma2025
  2. 2Facial Presentation of Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type: A Rare Case2025
  3. 3Plasmablastic Lymphoma Presenting With Multiple Cutaneous Nodules Mimicking Primary Cutaneous Marginal Zone Lymphoma2026
  4. 4Immune thrombocytopenia as a rare initial manifestation and complication of Hodgkin lymphoma: a Pediatric case report2025
  5. 5Case report: A case of intravascular large B-cell lymphoma and related literature review2025