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September 10, 2025ComputationOpen Access

Construction and Evaluation of a Domain-Related Risk Model for Prognosis Prediction in Colorectal Cancer

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Authors

XCXiangjun CuiYXYongqiang XingGLGuoqing Liu

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Overview

Analysis of domain-related genes shows significant prognostic value in colorectal cancer patients, indicating potential for personalized therapies.

Key Points

  • A prognostic signature based on four domain-related genes shows potential in predicting colorectal cancer outcomes.
  • Patients with differing risk groups exhibited significant variations in survival and immune response patterns.
  • The model was developed using CRC data from GSE39582 and TCGA datasets with LASSO-COX regression.
  • Identifying these genes may enhance personalized treatment strategies and improve patient outcomes.

Cite This Study

Cui et al. (2025) studied this question.

synapsesocial.com/papers/68c2416eb210217d6479ee92https://doi.org/10.3390/computation13070171
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  4. 4The Role of Epigenetic Biomarkers as Diagnostic, Predictive and Prognostic Factors in Colorectal Cancer2025
  5. 5The construction of a prognostic nomogram model for colorectal cancer and the prediction of immune characteristics and immune treatment responses based on the bioinformatics analysis of soluble mediator-related genes.2025