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September 10, 2025Asian Journal of Pharmaceutical Research

Advancing Diabetic Wound Care with Platelet Rich Plasma: A Systematic Review of Mechanisms and Therapeutic Potential

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Authors

BDB DharaniASA SUBA

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Overview

Systematic review reveals platelet rich plasma improves wound healing in diabetic foot ulcers, suggesting significant therapeutic potential.

Key Points

  • Platelet rich plasma therapy significantly enhances wound healing in diabetic foot ulcers, reducing amputation risks.
  • Key mechanisms include growth factor-driven angiogenesis, inflammation modulation, and antibacterial properties.
  • Cohort studies and observational studies were reviewed, revealing diverse impacts of PRP on diabetic ulcers.
  • This systematic review highlights the need for further research to optimize PRP's clinical applications in wound care.

Cite This Study

Dharani et al. (2025) studied this question.

synapsesocial.com/papers/68c2409bb210217d6479b82dhttps://doi.org/10.52711/2231-5691.2025.00053
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet-Rich Plasma for Wound Healing in Diabetic Patients2025 · 4 citations
  2. 2Platelet-rich plasma may accelerate diabetic wound healing by modulating epithelial/endothelial-mesenchymal transition through inhibiting reactive oxygen species-mediated oxidative stress2025 · 9 citations
  3. 3Successful Management of Diabetic Foot Ulcer Complicated by Osteomyelitis Using Platelet-Rich Plasma Therapy: A Case Report2025
  4. 4Comparison of Autologous Platelet-Rich Plasma (PRP)-Soaked Dressing vs. Saline-Soaked Dressing in the Healing of Diabetic Foot Ulcer2025
  5. 5Evidence Based Efficacy of Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) in Acute and Chronic Wound Healing: A Retrospective Case Series2025