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August 11, 2025Frontiers in Bioengineering and BiotechnologyOpen Access

Platelet-rich plasma may accelerate diabetic wound healing by modulating epithelial/endothelial-mesenchymal transition through inhibiting reactive oxygen species-mediated oxidative stress

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Authors

YLY LiBCBiao ChengJTJu Tian

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Overview

Hypothesis explores platelet-rich plasma's impact on reactive oxygen species and epithelial mesenchymal transition in diabetic wounds.

Key Points

  • Platelet-rich plasma (PRP) may enhance diabetic wound healing by reducing oxidative stress and accelerating repair mechanisms.
  • The proposed mechanisms for PRP's effect include decreasing reactive oxygen species and promoting crucial cellular processes such as angiogenesis.
  • This analysis focuses on PRP's potential to modulate epithelial and endothelial-mesenchymal transition (EMT/EndMT) dynamics in diabetic wounds.
  • Investigating PRP's role may provide insights into therapeutic strategies for diabetes-related oxidative stress conditions.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68af2695cf1dd9ea359e24ffhttps://doi.org/10.3389/fbioe.2025.1623780
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