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October 27, 2025Biological and Clinical Sciences Research Journal

Comparison of Autologous Platelet-Rich Plasma (PRP)-Soaked Dressing vs. Saline-Soaked Dressing in the Healing of Diabetic Foot Ulcer

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Authors

HGHafiz Saad GulzarMIMuhammad Arslan IqbalMGMuhammad Azeem Gulzar

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Overview

Randomized controlled trial shows PRP dressing improves healing by 23% in diabetic foot ulcers, indicating better outcomes.

Key Points

  • Complete healing was achieved in 86.7% of the PRP group versus 64.0% for saline, highlighting superior efficacy.
  • The mean ulcer area reduced to 0.9 cm² with PRP and 2.7 cm² with saline after six weeks, indicating significant improvement.
  • Participants were adult patients with diabetic foot ulcers, treated over six weeks at a hospital in Pakistan.
  • PRP offers a biologically active alternative to saline dressings, suggesting potential for wider application in wound care.

Cite This Study

Gulzar et al. (2025) studied this question.

synapsesocial.com/papers/68ff87e2c8c50a61f2bdd02fhttps://doi.org/10.54112/bcsrj.v6i5.2032
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet-Rich Plasma for Wound Healing in Diabetic Patients2025 · 4 citations
  2. 2Advancing Diabetic Wound Care with Platelet Rich Plasma: A Systematic Review of Mechanisms and Therapeutic Potential2025 · 1 citations
  3. 3Successful Management of Diabetic Foot Ulcer Complicated by Osteomyelitis Using Platelet-Rich Plasma Therapy: A Case Report2025
  4. 4Evidence Based Efficacy of Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) in Acute and Chronic Wound Healing: A Retrospective Case Series2025
  5. 5The contribution of platelet-rich plasma in the management of leg ulcers2026