September 10, 2025Archiv Euromedica

Vitamin D in Immunomodulation: A Factor in the Pathogenesis of Food Allergies

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Vitamin D contributes to immune tolerance, reinforcing regulatory T-cell responses and epithelial barrier function.
Research indicates vitamin D deficiency may increase susceptibility to food sensitization, particularly in early childhood.
A narrative review covers findings from 32 publications on vitamin D's role in food allergy from 2010 to 2024.
Current evidence is heterogeneous and mostly from preclinical studies, indicating a need for human clinical trials.

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Narrative review synthesizes evidence on vitamin D's immunomodulatory effects in food allergy, suggesting potential clinical implications.

Piśkiewicz et al. (2025) studied this question.

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Narrative review synthesizes evidence on vitamin D's immunomodulatory effects in food allergy, suggesting potential clinical implications.