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September 10, 2025MicroorganismsOpen Access

From Hue to Health: Exploring the Therapeutic Potential of Plant-Pigment-Enriched Extracts

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Authors

AEAzza S. El-DemerdashASAmira E. SehimAAAbeer A. Altamimi

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Overview

This study explores Hibiscus sabdariffa's antimicrobial and antibiofilm activity, suggesting a dual role against AMR and cancer.

Key Points

  • Hibiscus sabdariffa exhibited broad-spectrum antimicrobial and significant antibiofilm activity against resistant pathogens, suggesting its versatility.
  • Key compounds like Cyanidin-3-O-glucoside interacted favorably with bacterial proteins, enhancing its potential as an antimicrobial agent.
  • Chemical profiling revealed anthocyanin glucosides and non-pigment compounds, indicating a diverse range of bioactive components.
  • Sub-inhibitory concentrations of H. sabdariffa showed selective cytotoxicity against MCF-7 breast cancer cells, underscoring its potential in cancer therapy.

Cite This Study

El-Demerdash et al. (2025) studied this question.

synapsesocial.com/papers/68c2409bb210217d6479b272https://doi.org/10.3390/microorganisms13081818
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phytochemical, Antimicrobial and Antioxidant Evaluation of Hibiscus rosa sinensis Extract2025
  2. 2Toxicological Evaluation, Ultrasound‐Assisted Phytochemicals, Antioxidant, <scp>GC</scp> – <scp>MS</scp> , <scp>FTIR</scp> , and In Vivo Analysis of <scp> <i>Hibiscus rosa‐sinensis</i> </scp> Flowers2025 · 5 citations
  3. 3Evaluation of Hibiscus sabdariffa L. Extract's Antioxidant Activity and its Potential to Mitigate Chlorpyrifos-Induced Oxidative Stress in Adult Rats.2025
  4. 4Anti-staphylococcal activity, antibiotic-resistance modulation effects and action of Harungana madagascariensis (Hypericaceae) fruit extracts on the antioxidant system of multidrug-resistant Staphylococcus aureus2025
  5. 5Quercetin-3'-O-glucoside and delphinidin-3-O-sambubioside from Hibiscus sabdariffa Linn.: A molecular docking study against pathogen-associated molecular patterns and Toll-like receptors2025